Alexander Egilman, BA

Alexander Egilman, BA

Senior Research Assistant

Alexander Egilman is a Senior Research Assistant with PORTAL. His research focuses on laws, policies, and anticompetitive practices that affect patient access to affordable, safe, and innovative treatments. His work has appeared in JAMA, Annals of Internal Medicine, The BMJ, and The New York Times.

Egilman is a graduate of Haverford College.

Featured Work

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Added Therapeutic Benefit of Top-Selling Brand-Name Drugs in Medicare

Egilman AC, Rome BN, Kesselheim AS - JAMA

  • Price, Value, and Access
  • Regulation and Clinical Evidence
More than half of the top‑selling brand‑name drugs in Medicare provided little or no added therapeutic benefit compared with existing treatments, yet accounted for a large share of Medicare spending. These findings support using comparative effectiveness evidence in Medicare price negotiations.
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Frequency of Approval and Marketing of Biosimilars with a Skinny Label and Associated Medicare Savings

Egilman AC, Van de Wiele VL, Rome BN, Darrow JJ, Tu SS, Kesselheim AS, Sarpatwari A - JAMA Internal Medicine

  • Innovation Incentives and Competition
  • Price, Value, and Access
  • Regulation and Clinical Evidence
Between 2015 and 2021, 67% of biosimilars were approved with skinny labels, enabling earlier competition before all patents expired on the originator biologic expired. This pathway generated an estimated $1.5 billion in Medicare savings, highlight the value of this pathway amid increasing legal threats.
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Estimated Medicare Part B Savings From Inflationary Rebates

Egilman AC, Kesselheim AS, Rome BN - JAMA

  • Price, Value, and Access
If Medicare inflationary rebates had applied from 2018 to 2020, Medicare Part B drug spending would have been reduced by roughly 3%. The largest savings came from biologics and rare-disease drugs with prices rising faster than inflation.
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