Reporting Bias in Clinical Trials: Progress Toward Transparency and Next Steps

Mitra-Majumdar M, Kesselheim AS - PLOS Medicine

  • Regulation and Clinical Evidence

Summary:

The authors assess progress in addressing reporting bias in clinical trials noting that while regulatory requirements like ClinicalTrials.gov have improved transparency, studies still find that published literature overstates drug efficacy compared with FDA analyses.

VIEW SOURCE

Recent Work from PORTAL

Talk bubble graphics representing commentary and opinion.

How Congress Can Fix Expert Advisory Committees

Daval CJR, Kesselheim AS - STAT

  • Regulation and Clinical Evidence
Simple graphic of magnifying glass examining papers to signify reviewing research publications.

International Regulatory Status and Reimbursement Recommendations of Haematological Malignancy Drugs Withdrawn from the FDA Accelerated Approval Pathway

Mulsant SS, Kesselheim AS, Naci H - Journal of Cancer Policy

  • Price, Value, and Access
  • Regulation and Clinical Evidence
Talk bubble graphics representing commentary and opinion.

Politics and the Patient Encounter, in Dire Times

Avorn J - MedPage Today

  • Regulation and Clinical Evidence