Kesselheim AS, Avorn J - Washington Post
The pharmaceutical industry’s claim that allowing Medicare to negotiate drug prices would devastate innovationis contradicted by evidence showing that publicly funded research drives most transformative drug discoveries, that large manufacturers spend far more on marketing and buybacks than R&D, and that unconstrained pricing actually incentivizes development of low-risk, minimally innovative products. The authors contend that value-based price negotiation would reward genuinely beneficial drugs while discouraging therapeutically marginal ones, and warn that pharmaceutical lobbying and campaign contributions are the real forces behind congressional opposition to reform.
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Eisenkraft Klein D, Kesselheim AS - Clinical Pharmacology & Therapeutics
Cai CL, Bucha S, Kesselheim AS, Rome BN - Journal of General Internal Medicine
Chen NC, Bullement A, Zemplenyi AT, O'Bryant CL, Kaizer AM, Anderson KE, McQueen RB - PharmacoEconomics Open