Improving Antibiotic Markets for Long-Term Sustainability

The authors examine the challenges facing antibiotic markets, where the unique dynamics of antimicrobial resistance combined with the need for stewardship that limits the volume of new antibiotic prescriptions create commercial disincentives for development that standard market-based approaches fail to address. They propose reforms to improve antibiotic market sustainability through mechanisms that delink revenues from sales volume, ensuring adequate returns for innovative products while preserving their long-term effectiveness through appropriate use.