Physician Experiences with and Perspectives on Clozapine Prescribing

Clozapine, an effective therapy for treatment-resistant schizophrenia, had a risk evaluation and mitigation strategy (REMS) program in place to manage the risk of agranulocytosis. In a survey of nearly 200 physicians, two-thirds viewed the REMS program positively, though some physicians called for more educational materials and raised concerns about delays in patient access due to required laboratory testing.